So, coronavirus...

Where goats go to escape
Lobby
Posts: 1805
Joined: Mon Jul 06, 2020 7:34 pm

Saint wrote: Tue Apr 13, 2021 7:54 pm
BnM wrote: Tue Apr 13, 2021 7:39 pm Also as we don't manufacture or finish Pfizer what would be the point of the EU sending us 9m Pfizer and demanding 9m AZ in return. It's interesting the Pfizer contracts haven't been questioned once AFAICS
Well, that's never really been explained. But Pfizer themselves have pointed out to the EU that if the EU blocks exports to the UK then the UK's natural reaction might be to shit down component export to Pfizer. The thing about mRNA vaccines is that they;re close to being synthetic (predictable) production process rather than a biological (unpredictable) process, but for the moment at least they require complex supply chains involving many countries, unless you're the size of the US. Curevac mRNA when it comes online will be an mRNA completely manufactured in the UK AFAIK.
I think one of the reason for the EU’s demand for UK AZ vaccines is that AZ’s contract with the EU specifies that all vaccines will be manufactured in the EU, but includes provision for them to be supplied from elsewhere, including the UK, under certain circumstances. An additional complication is that, whereas AZ has to seek permission from the EU to supply from other countries, the UK is exempt from this provision, which could suggest that the UK is being treated as more equivalent to an EU based supplier. Hence, when AZ couldn’t meet expectations from its EU-based facilities, the EU demanded that it make up the shortfall from its UK facilities.

The UK doesn’t manufacture the Pfizer vaccine so they can’t really demand we supply these. When the EU first passed its laws restricting vaccine exports, there was an expectation that they might halt Pfizer vaccines as well, but Pfizer very quickly informed the German govt of the implications of doing this, and so Pfizer was quickly put off limits for these controls.
User avatar
Saint
Posts: 2274
Joined: Tue Jun 30, 2020 8:38 am

Lobby wrote: Tue Apr 13, 2021 9:40 pm
Saint wrote: Tue Apr 13, 2021 7:54 pm
BnM wrote: Tue Apr 13, 2021 7:39 pm Also as we don't manufacture or finish Pfizer what would be the point of the EU sending us 9m Pfizer and demanding 9m AZ in return. It's interesting the Pfizer contracts haven't been questioned once AFAICS
Well, that's never really been explained. But Pfizer themselves have pointed out to the EU that if the EU blocks exports to the UK then the UK's natural reaction might be to shit down component export to Pfizer. The thing about mRNA vaccines is that they;re close to being synthetic (predictable) production process rather than a biological (unpredictable) process, but for the moment at least they require complex supply chains involving many countries, unless you're the size of the US. Curevac mRNA when it comes online will be an mRNA completely manufactured in the UK AFAIK.
I think one of the reason for the EU’s demand for UK AZ vaccines is that AZ’s contract with the EU specifies that all vaccines will be manufactured in the EU, but includes provision for them to be supplied from elsewhere, including the UK, under certain circumstances. An additional complication is that, whereas AZ has to seek permission from the EU to supply from other countries, the UK is exempt from this provision, which could suggest that the UK is being treated as more equivalent to an EU based supplier. Hence, when AZ couldn’t meet expectations from its EU-based facilities, the EU demanded that it make up the shortfall from its UK facilities.

The UK doesn’t manufacture the Pfizer vaccine so they can’t really demand we supply these. When the EU first passed its laws restricting vaccine exports, there was an expectation that they might halt Pfizer vaccines as well, but Pfizer very quickly informed the German govt of the implications of doing this, and so Pfizer was quickly put off limits for these controls.
The AZ contract specifies that the theoretical two UK sites can be part of the production channel for the EU, but doesn't say anything about % that will be supplied or that they are required to supply the EU. The (unpublished) UK contract apparently specifies that UK production is for the UK unless or until supply exceeds demand, or something close to that effect. It also may or may not contain language about the UK's expectations on AZ for plants in the EU to supply the UK. It's actually very interesting given just how many people must have knowledge of that contract that it hasn't really leaked from either side - at a guess there are probably more than 100 people who have at least some knowledge of what the UK/AZ contract says, and the usual rule of thumb is that 3 people is enough to guarantee a leak - there's been insinuations, but by now you would have expected an unredacted copy to have hit the web.
User avatar
Hal Jordan
Posts: 4154
Joined: Tue Jun 30, 2020 12:48 pm
Location: Sector 2814

I see that the man tasked as Chief Investigator into whether the vaccines can be mixed is...Professor Snape.

If, when presenting his findings, he doesn't direct us to turn to page 394 I will be sorely disappointed.
User avatar
Saint
Posts: 2274
Joined: Tue Jun 30, 2020 8:38 am

Some interesting numbers...... ONS are reporting that approx 55% of all adults would test positive for antibodies as of end of March. This is almost certainly an undercount as the antibody test isn't massively sensitive, and obviously it doesn't cover T-Cell etc.#

And I just noticed on the Zoe app that they're estimating in my local area at least, active Covid cases are now as low as they were at the lowest point last summer and still dropping. All positive news, but we need a couple of weeks to be able to start guaging what impact the initial release from lockdown has had
User avatar
Sandstorm
Posts: 10886
Joined: Mon Jun 29, 2020 7:05 pm
Location: England

Saint wrote: Wed Apr 14, 2021 11:33 am Some interesting numbers...... ONS are reporting that approx 55% of all adults would test positive for antibodies as of end of March. This is almost certainly an undercount as the antibody test isn't massively sensitive, and obviously it doesn't cover T-Cell etc.#

And I just noticed on the Zoe app that they're estimating in my local area at least, active Covid cases are now as low as they were at the lowest point last summer and still dropping. All positive news, but we need a couple of weeks to be able to start guaging what impact the initial release from lockdown has had
Be interesting to see how many people will bother to go get tested now. Last year having a Covid test was a novelty and most people took the results seriously and isolated properly. I feel by now the novelty has worn off and with the risk of "passing on Covid to an elderly person and killing them" reduced, many people will just carry on despite having Covid symptoms.

"It's probably just a cold....I'm going to work/shops/gym anyway"
TheNatalShark
Posts: 1180
Joined: Sat Aug 22, 2020 4:35 pm

Sandstorm wrote: Wed Apr 14, 2021 12:40 pm
Saint wrote: Wed Apr 14, 2021 11:33 am Some interesting numbers...... ONS are reporting that approx 55% of all adults would test positive for antibodies as of end of March. This is almost certainly an undercount as the antibody test isn't massively sensitive, and obviously it doesn't cover T-Cell etc.#

And I just noticed on the Zoe app that they're estimating in my local area at least, active Covid cases are now as low as they were at the lowest point last summer and still dropping. All positive news, but we need a couple of weeks to be able to start guaging what impact the initial release from lockdown has had
Be interesting to see how many people will bother to go get tested now. Last year having a Covid test was a novelty and most people took the results seriously and isolated properly. I feel by now the novelty has worn off and with the risk of "passing on Covid to an elderly person and killing them" reduced, many people will just carry on despite having Covid symptoms.

"It's probably just a cold....I'm going to work/shops/gym anyway"
Aye, in Wandsworth we've been asked to do the surge testing for SA variant, and rugby club is asking everyone to do it and I suspect people will get told off if they don't.

But beyond that general chatter around taking tests is low vs last year from my circles.
User avatar
Saint
Posts: 2274
Joined: Tue Jun 30, 2020 8:38 am

Daily updates on testing by type and pillar can be found here https://coronavirus.data.gov.uk/details/testing
User avatar
tabascoboy
Posts: 6474
Joined: Tue Jun 30, 2020 8:22 am
Location: 曇りの街

Denmark has become the first European country to completely stop using the AstraZeneca vaccine due to rare blood clotting concerns - but it may not be forever.

The head of Denmark's health authority, Soren Brostrom says he is not ruling out using the vaccine again in the future, adding if Denmark was in a different situation right now and being affected by a third wave of the pandemic, Danish health authorities would not hesitate to use the vaccine.
User avatar
Saint
Posts: 2274
Joined: Tue Jun 30, 2020 8:38 am

Moderna have jsut tested a version of their vaccine targeting the SA variant, shown to produce the correct antibodies in mice
User avatar
Sandstorm
Posts: 10886
Joined: Mon Jun 29, 2020 7:05 pm
Location: England

Saint wrote: Wed Apr 14, 2021 4:55 pm Moderna have just tested a version of their vaccine targeting the SA variant, shown to produce the correct antibodies in mice
Noice
User avatar
Sandstorm
Posts: 10886
Joined: Mon Jun 29, 2020 7:05 pm
Location: England

Friend spoke with his Dad in India this morning and they are reporting 250k new Covid cases per day across the country!! :eek:
User avatar
Sards
Posts: 9291
Joined: Tue Jun 30, 2020 4:41 am

I expect there are a lot of posters here that have been chipped already.
User avatar
Raggs
Posts: 3698
Joined: Mon Jun 29, 2020 6:51 pm

Sandstorm wrote: Thu Apr 15, 2021 2:11 pm Friend spoke with his Dad in India this morning and they are reporting 250k new Covid cases per day across the country!! :eek:
India is going to have been a mess. Only something like 85% of deaths are reported to government *not* during a pandemic, something like only 25% of those have an actual doctor certified cause of death on their certificates, and even then we're mostly looking at the richer population.
Give a man a fire and he'll be warm for a day. Set a man on fire and he'll be warm for the rest of his life.
User avatar
Sards
Posts: 9291
Joined: Tue Jun 30, 2020 4:41 am

Do you think we can still save the world by reducing the population with Covid and the variants. I mean it looks pretty much farked to me....
User avatar
Raggs
Posts: 3698
Joined: Mon Jun 29, 2020 6:51 pm

Sards wrote: Thu Apr 15, 2021 2:31 pm Do you think we can still save the world by reducing the population with Covid and the variants. I mean it looks pretty much farked to me....
What would reducing the population do? There's not a food production problem in this world as it stands, there's an economic one. And economies aren't getting any better through covid.
Give a man a fire and he'll be warm for a day. Set a man on fire and he'll be warm for the rest of his life.
User avatar
JM2K6
Posts: 9802
Joined: Wed Jul 01, 2020 10:43 am

Saint wrote: Wed Apr 14, 2021 4:55 pm Moderna have jsut tested a version of their vaccine targeting the SA variant, shown to produce the correct antibodies in mice
Well that's shit - why are we vaccinating mice? Let the fuckers die
User avatar
Saint
Posts: 2274
Joined: Tue Jun 30, 2020 8:38 am

Oxford University study into Blood Clots post Covid and post vaccine - very high level
A study suggests the risk of getting rare blood clots is eight to 10 times higher after contracting coronavirus than it is for those who have been vaccinated against the disease.

Researchers at Oxford University (independent of the Oxford-AstraZeneca vaccine) said the risk of cerebral venous thrombosis (CVT) - an unusual blood clot in the brain also known as CVST (cerebral venous sinus thrombosis) - is around eight to 10 times higher after catching the virus than getting vaccinated with the BioNTech-Pfizer, Moderna or Oxford-AstraZeneca Covid jabs.

The researchers said people who have had Covid shouldn't be unduly worried by clots either.
User avatar
Sandstorm
Posts: 10886
Joined: Mon Jun 29, 2020 7:05 pm
Location: England

JM2K6 wrote: Thu Apr 15, 2021 2:48 pm
Saint wrote: Wed Apr 14, 2021 4:55 pm Moderna have jsut tested a version of their vaccine targeting the SA variant, shown to produce the correct antibodies in mice
Well that's shit - why are we vaccinating mice? Let the fuckers die
:lol:
User avatar
Sandstorm
Posts: 10886
Joined: Mon Jun 29, 2020 7:05 pm
Location: England

New Desi Covid variant frim India is looking very scary. Now a few dozen cases in London.

Awesome border controls yet again Boris!
User avatar
TB63
Posts: 4014
Joined: Mon Jun 29, 2020 9:11 pm
Location: Tinopolis

Sandstorm wrote: Fri Apr 16, 2021 11:45 am New Desi Covid variant frim India is looking very scary. Now a few dozen cases in London.

Awesome border controls yet again Boris!
<<<Stares suspiciously at Chicken Tikka in fridge>>>
User avatar
Hal Jordan
Posts: 4154
Joined: Tue Jun 30, 2020 12:48 pm
Location: Sector 2814

Sandstorm wrote: Fri Apr 16, 2021 11:45 am New Desi Covid variant frim India is looking very scary. Now a few dozen cases in London.

Awesome border controls yet again Boris!
Do we need a trade deal with them?

Plus our good friend Modi on the Axis of Fash.
Lobby
Posts: 1805
Joined: Mon Jul 06, 2020 7:34 pm

Hal Jordan wrote: Fri Apr 16, 2021 12:25 pm
Sandstorm wrote: Fri Apr 16, 2021 11:45 am New Desi Covid variant frim India is looking very scary. Now a few dozen cases in London.

Awesome border controls yet again Boris!
Do we need a trade deal with them?

Plus our good friend Modi on the Axis of Fash.
Interesting that while Bangladesh and Pakistan are on the UK travel red list countries, India hasn’t yet been added, despite its high rate of infections and nasty variants.

Boris is due to fly over there in 10 days time with a whole entourage of officials and lobbyists; be interesting to see if that goes ahead.
Biffer
Posts: 9142
Joined: Mon Jun 29, 2020 6:43 pm

Seems that the Pfizer and Moderna vaccines also cause blood clots

https://www.sciencemediacentre.org/expe ... influenza/

Come on Denmark, ban them.
And are there two g’s in Bugger Off?
User avatar
Sandstorm
Posts: 10886
Joined: Mon Jun 29, 2020 7:05 pm
Location: England

Lobby wrote: Fri Apr 16, 2021 12:31 pm
Hal Jordan wrote: Fri Apr 16, 2021 12:25 pm
Sandstorm wrote: Fri Apr 16, 2021 11:45 am New Desi Covid variant frim India is looking very scary. Now a few dozen cases in London.

Awesome border controls yet again Boris!
Do we need a trade deal with them?

Plus our good friend Modi on the Axis of Fash.
Interesting that while Bangladesh and Pakistan are on the UK travel red list countries, India hasn’t yet been added, despite its high rate of infections and nasty variants.

Boris is due to fly over there in 10 days time with a whole entourage of officials and lobbyists; be interesting to see if that goes ahead.
Good question for the 5pm Covid Show: "So Prime Minister, are you and your 100 lobbyists going to cancel your trade junket to India to save lives and protect the NHS?"
User avatar
Sandstorm
Posts: 10886
Joined: Mon Jun 29, 2020 7:05 pm
Location: England

Biffer wrote: Fri Apr 16, 2021 2:30 pm Seems that the Pfizer and Moderna vaccines also cause blood clots

https://www.sciencemediacentre.org/expe ... influenza/

Come on Denmark, ban them.
:lol: :clap:
User avatar
Fangle
Posts: 567
Joined: Tue Jun 30, 2020 3:25 pm

Pfizer have announced that possiby an annual booster shot will be required. Moderna are working on a combined covid/flu booster.
User avatar
Bullet
Posts: 296
Joined: Thu Jul 23, 2020 8:14 pm
Location: Wimborne, Dorset

Just booked my 2nd jab for the end of April.
With my Mother in law dying yesterday it's shaping up to be a good weekend
User avatar
Sandstorm
Posts: 10886
Joined: Mon Jun 29, 2020 7:05 pm
Location: England

Bullet wrote: Fri Apr 16, 2021 6:51 pm Just booked my 2nd jab for the end of April.
With my Mother in law dying yesterday it's shaping up to be a good weekend
:eek:
User avatar
Raggs
Posts: 3698
Joined: Mon Jun 29, 2020 6:51 pm

Sinovac only 80% effective at preventing death.

https://www.reuters.com/business/health ... 021-04-16/

85% against hospitalisation and 67% against symptomatic infection. This has to be taken with consideration that it's facing p1 strain a lot. Would be interesting to see if there's a good breakdown against strains.
Give a man a fire and he'll be warm for a day. Set a man on fire and he'll be warm for the rest of his life.
User avatar
Calculon
Posts: 1784
Joined: Mon Jun 29, 2020 7:25 pm

That's not bad, will be interesting to see how it compares to the pfizer
He said Chile's health ministry will shortly publish a real world study on the effectiveness of both vaccines rolled out in its population and appealed to Chileans to continue to participate in the vaccination programme.
User avatar
Fangle
Posts: 567
Joined: Tue Jun 30, 2020 3:25 pm

In Georgia they are struggling to get people vaccinated, especially in Deliverance mountain areas. So they have opened clinics to all comers. Just rock up and get your vaccinations.
User avatar
BnM
Posts: 977
Joined: Wed Jul 01, 2020 2:40 pm

Agnes Pannier-Runacher, the French industry minister, said it is 'highly probable' that the EU won't order any more AstraZeneca or Johnson & Johnson vaccines.
Europe is scheduled to receive 500million doses of AZ and J&J vaccines this year, but it is thought contract will not be renewed after that
No comment.
Glaston
Posts: 484
Joined: Tue Jun 30, 2020 8:35 am

In other news, Fiji vaccinated nearly 2% of its population on thursday with the AZ jab.


The EU and the Yanks can send the AZ jab they don't want to the COVAX set up.
User avatar
Raggs
Posts: 3698
Joined: Mon Jun 29, 2020 6:51 pm

Glaston wrote: Sat Apr 17, 2021 2:29 am In other news, Fiji vaccinated nearly 2% of its population on thursday with the AZ jab.


The EU and the Yanks can send the AZ jab they don't want to the COVAX set up.
The Yanks can't actually. Contract won't allow them.
Give a man a fire and he'll be warm for a day. Set a man on fire and he'll be warm for the rest of his life.
Glaston
Posts: 484
Joined: Tue Jun 30, 2020 8:35 am

Raggs wrote: Sat Apr 17, 2021 8:34 am
Glaston wrote: Sat Apr 17, 2021 2:29 am In other news, Fiji vaccinated nearly 2% of its population on thursday with the AZ jab.


The EU and the Yanks can send the AZ jab they don't want to the COVAX set up.
The Yanks can't actually. Contract won't allow them.
So the vaccine is sitting in a USA warehouse slowly running out of bb4 date.

Meanwhile the Chinese are offering their vaccine to all and sundry.

Wonder who will win the Global soft power battle?
User avatar
Raggs
Posts: 3698
Joined: Mon Jun 29, 2020 6:51 pm

Glaston wrote: Sat Apr 17, 2021 10:27 am
Raggs wrote: Sat Apr 17, 2021 8:34 am
Glaston wrote: Sat Apr 17, 2021 2:29 am In other news, Fiji vaccinated nearly 2% of its population on thursday with the AZ jab.


The EU and the Yanks can send the AZ jab they don't want to the COVAX set up.
The Yanks can't actually. Contract won't allow them.
So the vaccine is sitting in a USA warehouse slowly running out of bb4 date.

Meanwhile the Chinese are offering their vaccine to all and sundry.

Wonder who will win the Global soft power battle?
That's not what I said. American companies can sell who they want to. But anything bought by the USA can only be used in US territories and cannot be exported elsewhere.
Give a man a fire and he'll be warm for a day. Set a man on fire and he'll be warm for the rest of his life.
User avatar
Sandstorm
Posts: 10886
Joined: Mon Jun 29, 2020 7:05 pm
Location: England

Hawaiian Islands are vaccinating 18-25 year olds this week with Pfiser. 16-17 year olds pencilled in for 1 June.
User avatar
Saint
Posts: 2274
Joined: Tue Jun 30, 2020 8:38 am

Raggs wrote: Sat Apr 17, 2021 10:28 am
Glaston wrote: Sat Apr 17, 2021 10:27 am
Raggs wrote: Sat Apr 17, 2021 8:34 am

The Yanks can't actually. Contract won't allow them.
So the vaccine is sitting in a USA warehouse slowly running out of bb4 date.

Meanwhile the Chinese are offering their vaccine to all and sundry.

Wonder who will win the Global soft power battle?
That's not what I said. American companies can sell who they want to. But anything bought by the USA can only be used in US territories and cannot be exported elsewhere.
I thought its was more that the US had part funded AZ production in the US, and therefore every export requires Presidential sign-off
User avatar
Raggs
Posts: 3698
Joined: Mon Jun 29, 2020 6:51 pm

Saint wrote: Sat Apr 17, 2021 4:08 pm
Raggs wrote: Sat Apr 17, 2021 10:28 am
Glaston wrote: Sat Apr 17, 2021 10:27 am

So the vaccine is sitting in a USA warehouse slowly running out of bb4 date.

Meanwhile the Chinese are offering their vaccine to all and sundry.

Wonder who will win the Global soft power battle?
That's not what I said. American companies can sell who they want to. But anything bought by the USA can only be used in US territories and cannot be exported elsewhere.
I thought its was more that the US had part funded AZ production in the US, and therefore every export requires Presidential sign-off
I posted a new article a while back saying contracts with vaccine companies says anything sold to US must be used within us territories.
Give a man a fire and he'll be warm for a day. Set a man on fire and he'll be warm for the rest of his life.
User avatar
Saint
Posts: 2274
Joined: Tue Jun 30, 2020 8:38 am

Raggs wrote: Sat Apr 17, 2021 4:51 pm
Saint wrote: Sat Apr 17, 2021 4:08 pm
Raggs wrote: Sat Apr 17, 2021 10:28 am

That's not what I said. American companies can sell who they want to. But anything bought by the USA can only be used in US territories and cannot be exported elsewhere.
I thought its was more that the US had part funded AZ production in the US, and therefore every export requires Presidential sign-off
I posted a new article a while back saying contracts with vaccine companies says anything sold to US must be used within us territories.
To the best of my knowledge, over two thirds of US production from AZ has been contracted to countries other than US (primarily Canada and Mexico). The trouble is that AZ can't even send what they're contracted to to either country without a Presidential signature, because some of the production capability in the US was funded under there Defense Procurement Act. There's 30 million plus doses sat in the US that wont last forever. 4 million odd were released to Canada and Mexico last month under a reciprocal agreement that said they would be replace, but even that caused issues internally in the US. There's a very real chance that the majority of what has alreay been produced will be allowed to go to waste.
Post Reply